Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
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Co-expression
Experiments
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[Homology]
Score
phoPAlkaline phosphatase synthesis transcriptional regulatory protein PhoP. (228 aa)    
Predicted Functional Partners:
phoR_1
Alkaline phosphatase synthesis sensor protein PhoR.
 0.996
OPJ56036.1
Blue-light-activated protein.
 
 0.982
kinE
Sporulation kinase E.
 
 
 0.931
yycG
Sensor histidine kinase YycG.
 0.914
phoR_2
Alkaline phosphatase synthesis sensor protein PhoR.
 0.885
nrdR
Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
     
 0.828
spo0F
Sporulation initiation phosphotransferase F.
  
  
  0.807
hndC_1
NADP-reducing hydrogenase subunit HndC.
   
 
 0.800
hndC_2
NADP-reducing hydrogenase subunit HndC.
   
 
 0.800
hndA_1
NADP-reducing hydrogenase subunit HndA.
   
 
 0.777
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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