Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
uraAUracil permease. (414 aa)    
Predicted Functional Partners:
pyrR
Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
  
  
 0.985
pyrC_1
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
  
 0.970
pyrB
Aspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.969
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.955
pyrD
Dihydroorotate dehydrogenase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
  
  
 0.947
carB
Carbamoyl-phosphate synthase large chain.
  
  
 0.931
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
  
 0.848
carA
Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.
  
  
 0.834
purL
Phosphoribosylformylglycinamidine synthase 2.
  
  
 0.828
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.733
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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