Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)    
Predicted Functional Partners:
pduL
Phosphate propanoyltransferase; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.
  
 0.992
nifJ
Pyruvate-flavodoxin oxidoreductase.
    
 0.970
adhE
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
    
 0.958
pta_2
Phosphate acetyltransferase.
 
 0.939
pta_1
Phosphate acetyltransferase.
 
 0.936
pflB
Formate acetyltransferase.
  
 
 0.794
thlA
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
    
 0.792
acdA
acyl-CoA dehydrogenase.
     
 0.788
glcB
PTS system glucoside-specific EIICBA component.
     
 0.722
ptsG
PTS system glucose-specific EIICBA component.
     
 0.722
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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