STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xerD_1Tyrosine recombinase XerD; Belongs to the 'phage' integrase family. (294 aa)    
Predicted Functional Partners:
OPJ56964.1
Hypothetical protein.
  
    0.757
nifJ
Pyruvate-flavodoxin oxidoreductase.
    
  0.644
nudF
ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.
  
    0.576
OPJ56962.1
Hypothetical protein.
       0.566
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
  
    0.561
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.560
mraY_2
phospho-N-acetylmuramoyl-pentapeptide- transferase.
       0.542
prs_1
Ribose-phosphate pyrophosphokinase.
  
    0.541
OPJ56960.1
Undecaprenyl-phosphate mannosyltransferase.
       0.534
spoIIIE
DNA translocase SpoIIIE; Belongs to the FtsK/SpoIIIE/SftA family.
  
   
 0.530
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.