| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OPJ57046.1 | aroF | CLOTH_03280 | CLOTH_03330 | Hypothetical protein. | Phospho-2-dehydro-3-deoxyheptonate aldolase. | 0.773 |
| OPJ57046.1 | folE | CLOTH_03280 | CLOTH_03290 | Hypothetical protein. | GTP cyclohydrolase 1. | 0.815 |
| OPJ57046.1 | folK | CLOTH_03280 | CLOTH_03320 | Hypothetical protein. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.796 |
| OPJ57046.1 | folP | CLOTH_03280 | CLOTH_03300 | Hypothetical protein. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.805 |
| OPJ57046.1 | ilvE | CLOTH_03280 | CLOTH_03270 | Hypothetical protein. | Branched-chain-amino-acid aminotransferase. | 0.859 |
| OPJ57046.1 | pabA | CLOTH_03280 | CLOTH_03250 | Hypothetical protein. | Aminodeoxychorismate/anthranilate synthase component 2. | 0.826 |
| OPJ57046.1 | pabB | CLOTH_03280 | CLOTH_03260 | Hypothetical protein. | Aminodeoxychorismate synthase component 1. | 0.846 |
| aroC | aroF | CLOTH_01200 | CLOTH_03330 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Phospho-2-dehydro-3-deoxyheptonate aldolase. | 0.857 |
| aroC | guaA | CLOTH_01200 | CLOTH_11700 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.749 |
| aroC | ilvE | CLOTH_01200 | CLOTH_03270 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Branched-chain-amino-acid aminotransferase. | 0.573 |
| aroC | pabA | CLOTH_01200 | CLOTH_03250 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Aminodeoxychorismate/anthranilate synthase component 2. | 0.942 |
| aroC | pabB | CLOTH_01200 | CLOTH_03260 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Aminodeoxychorismate synthase component 1. | 0.960 |
| aroC | ydiB | CLOTH_01200 | CLOTH_13750 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Quinate/shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.971 |
| aroF | OPJ57046.1 | CLOTH_03330 | CLOTH_03280 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Hypothetical protein. | 0.773 |
| aroF | aroC | CLOTH_03330 | CLOTH_01200 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.857 |
| aroF | folE | CLOTH_03330 | CLOTH_03290 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | GTP cyclohydrolase 1. | 0.785 |
| aroF | folK | CLOTH_03330 | CLOTH_03320 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.940 |
| aroF | folP | CLOTH_03330 | CLOTH_03300 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.793 |
| aroF | ilvE | CLOTH_03330 | CLOTH_03270 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Branched-chain-amino-acid aminotransferase. | 0.864 |
| aroF | pabA | CLOTH_03330 | CLOTH_03250 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Aminodeoxychorismate/anthranilate synthase component 2. | 0.903 |