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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
OPJ57073.16-pyruvoyl tetrahydropterin synthase. (140 aa)    
Predicted Functional Partners:
queE
7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.999
queC
7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
 
  
 0.997
folE
GTP cyclohydrolase 1.
  
 
 0.972
OPJ57071.1
2-hydroxyglutaryl-CoA dehydratase, D-component.
 
    0.907
OPJ57056.1
Putative GTP cyclohydrolase 1 type 2; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
    
  0.870
pflA_3
Pyruvate formate-lyase 1-activating enzyme; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
  
 
 0.834
fldI_2
R-phenyllactate dehydratase activator.
 
     0.784
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.644
OPJ57077.1
Sepiapterin reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
  0.638
cysS
cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.610
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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