pyrH protein (Clostridium thermoalcaliphilum)

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Score

pyrH

Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (237 aa)

Predicted Functional Partners:

frr

0.993

tsf

0.980

upp

0.977

pyrR

0.976

thrZ_2

0.949

rpsB

0.944

surE

0.939

pyrF

0.938

udk

0.883

guaA

0.869

Your Current Organism:

Clostridium thermoalcaliphilum

NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
frr	guaA	CLOTH_04050	CLOTH_11700	Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.768
frr	pyrH	CLOTH_04050	CLOTH_04040	Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.993
frr	rpsB	CLOTH_04050	CLOTH_04020	Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.995
frr	thrZ_2	CLOTH_04050	CLOTH_09810	Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	threonine--tRNA ligase 2.	0.845
frr	tsf	CLOTH_04050	CLOTH_04030	Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.996
guaA	frr	CLOTH_11700	CLOTH_04050	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	0.768
guaA	pyrF	CLOTH_11700	CLOTH_11880	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.	0.805
guaA	pyrH	CLOTH_11700	CLOTH_04040	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.869
guaA	pyrR	CLOTH_11700	CLOTH_01760	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.	0.684
guaA	rpsB	CLOTH_11700	CLOTH_04020	GMP synthase; Catalyzes the synthesis of GMP from XMP.	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.822
guaA	surE	CLOTH_11700	CLOTH_04920	GMP synthase; Catalyzes the synthesis of GMP from XMP.	5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.976
guaA	thrZ_2	CLOTH_11700	CLOTH_09810	GMP synthase; Catalyzes the synthesis of GMP from XMP.	threonine--tRNA ligase 2.	0.872
guaA	tsf	CLOTH_11700	CLOTH_04030	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.710
guaA	udk	CLOTH_11700	CLOTH_02550	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Uridine kinase.	0.444
guaA	upp	CLOTH_11700	CLOTH_15740	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.976
pyrF	guaA	CLOTH_11880	CLOTH_11700	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.805
pyrF	pyrH	CLOTH_11880	CLOTH_04040	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.938
pyrF	pyrR	CLOTH_11880	CLOTH_01760	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.	Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.	0.988
pyrF	surE	CLOTH_11880	CLOTH_04920	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.	5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.899
pyrF	thrZ_2	CLOTH_11880	CLOTH_09810	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.	threonine--tRNA ligase 2.	0.903