pspA_1 protein (Clostridium thermoalcaliphilum)

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Score

pspA_1

Phosphoserine phosphatase 1; Belongs to the phosphoglycerate mutase family. (202 aa)

Predicted Functional Partners:

glyA

0.885

tdcB

0.879

sdhA

0.873

cysE_1

0.857

cobS

0.798

sdhB

0.780

ybbH_1

0.717

plsC

0.670

cobT

0.662

cmk

0.658

Your Current Organism:

Clostridium thermoalcaliphilum

NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cmk	plsC	CLOTH_04840	CLOTH_04830	Cytidylate kinase.	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	0.965
cmk	pspA_1	CLOTH_04840	CLOTH_04860	Cytidylate kinase.	Phosphoserine phosphatase 1; Belongs to the phosphoglycerate mutase family.	0.658
cmk	ybbH_1	CLOTH_04840	CLOTH_04870	Cytidylate kinase.	Putative HTH-type transcriptional regulator YbbH.	0.526
cobS	cobT	CLOTH_09670	CLOTH_11800	Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).	0.969
cobS	pspA_1	CLOTH_09670	CLOTH_04860	Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.	Phosphoserine phosphatase 1; Belongs to the phosphoglycerate mutase family.	0.798
cobT	cobS	CLOTH_11800	CLOTH_09670	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).	Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.	0.969
cobT	pspA_1	CLOTH_11800	CLOTH_04860	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).	Phosphoserine phosphatase 1; Belongs to the phosphoglycerate mutase family.	0.662
cysE_1	glyA	CLOTH_18830	CLOTH_00660	Serine acetyltransferase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.903
cysE_1	pspA_1	CLOTH_18830	CLOTH_04860	Serine acetyltransferase.	Phosphoserine phosphatase 1; Belongs to the phosphoglycerate mutase family.	0.857
cysE_1	sdhA	CLOTH_18830	CLOTH_13300	Serine acetyltransferase.	L-serine dehydratase, alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.874
cysE_1	sdhB	CLOTH_18830	CLOTH_13290	Serine acetyltransferase.	L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.874
cysE_1	tdcB	CLOTH_18830	CLOTH_13270	Serine acetyltransferase.	L-threonine dehydratase catabolic TdcB.	0.872
glyA	cysE_1	CLOTH_00660	CLOTH_18830	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Serine acetyltransferase.	0.903
glyA	pspA_1	CLOTH_00660	CLOTH_04860	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Phosphoserine phosphatase 1; Belongs to the phosphoglycerate mutase family.	0.885
glyA	sdhA	CLOTH_00660	CLOTH_13300	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	L-serine dehydratase, alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.961
glyA	sdhB	CLOTH_00660	CLOTH_13290	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.961
glyA	tdcB	CLOTH_00660	CLOTH_13270	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	L-threonine dehydratase catabolic TdcB.	0.890
plsC	cmk	CLOTH_04830	CLOTH_04840	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	Cytidylate kinase.	0.965
plsC	pspA_1	CLOTH_04830	CLOTH_04860	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	Phosphoserine phosphatase 1; Belongs to the phosphoglycerate mutase family.	0.670
plsC	ybbH_1	CLOTH_04830	CLOTH_04870	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	Putative HTH-type transcriptional regulator YbbH.	0.516