korA_1 protein (Clostridium thermoalcaliphilum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

korA_1

2-oxoglutarate oxidoreductase subunit KorA. (377 aa)

Predicted Functional Partners:

nifJ

0.999

korB_1

0.998

porC_1

0.993

korB_2

0.989

ndhI_1

0.958

hndA_1

0.937

porC_2

0.919

pyk

0.889

adhE

0.822

cfiB

0.812

Your Current Organism:

Clostridium thermoalcaliphilum

NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
adhE	cfiB	CLOTH_11210	CLOTH_05770	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.945
adhE	hndA_1	CLOTH_11210	CLOTH_04650	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	NADP-reducing hydrogenase subunit HndA.	0.974
adhE	korA_1	CLOTH_11210	CLOTH_04900	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	2-oxoglutarate oxidoreductase subunit KorA.	0.822
adhE	korB_1	CLOTH_11210	CLOTH_04890	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	2-oxoglutarate oxidoreductase subunit KorB.	0.812
adhE	korB_2	CLOTH_11210	CLOTH_20280	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	2-oxoglutarate oxidoreductase subunit KorB.	0.812
adhE	ndhI_1	CLOTH_11210	CLOTH_04910	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	NAD(P)H-quinone oxidoreductase subunit I.	0.725
adhE	nifJ	CLOTH_11210	CLOTH_01250	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Pyruvate-flavodoxin oxidoreductase.	0.974
adhE	porC_1	CLOTH_11210	CLOTH_04880	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Pyruvate synthase subunit PorC.	0.753
adhE	porC_2	CLOTH_11210	CLOTH_20290	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Pyruvate synthase subunit PorC.	0.753
adhE	pyk	CLOTH_11210	CLOTH_18010	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.968
cfiB	adhE	CLOTH_05770	CLOTH_11210	2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.945
cfiB	hndA_1	CLOTH_05770	CLOTH_04650	2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	NADP-reducing hydrogenase subunit HndA.	0.870
cfiB	korA_1	CLOTH_05770	CLOTH_04900	2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	2-oxoglutarate oxidoreductase subunit KorA.	0.812
cfiB	korB_1	CLOTH_05770	CLOTH_04890	2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	2-oxoglutarate oxidoreductase subunit KorB.	0.812
cfiB	korB_2	CLOTH_05770	CLOTH_20280	2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	2-oxoglutarate oxidoreductase subunit KorB.	0.882
cfiB	nifJ	CLOTH_05770	CLOTH_01250	2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Pyruvate-flavodoxin oxidoreductase.	0.949
cfiB	pyk	CLOTH_05770	CLOTH_18010	2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.972
hndA_1	adhE	CLOTH_04650	CLOTH_11210	NADP-reducing hydrogenase subunit HndA.	Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.974
hndA_1	cfiB	CLOTH_04650	CLOTH_05770	NADP-reducing hydrogenase subunit HndA.	2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.870
hndA_1	korA_1	CLOTH_04650	CLOTH_04900	NADP-reducing hydrogenase subunit HndA.	2-oxoglutarate oxidoreductase subunit KorA.	0.937