STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pflA_1Pyruvate formate-lyase 1-activating enzyme. (278 aa)    
Predicted Functional Partners:
pflB
Formate acetyltransferase.
 
  
 0.956
OPJ57221.1
Hypothetical protein.
 
  
 0.931
adhE
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
  
 0.868
nifJ
Pyruvate-flavodoxin oxidoreductase.
     
 0.684
cobU
Bifunctional adenosylcobalamin biosynthesis protein CobU.
   
    0.672
mdh
NAD-dependent methanol dehydrogenase.
 
  
 0.630
pflA_3
Pyruvate formate-lyase 1-activating enzyme; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
 
     0.480
hndA_1
NADP-reducing hydrogenase subunit HndA.
      
 0.459
OPJ57222.1
Hypothetical protein.
       0.432
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.429
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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