STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sacX_1Negative regulator of SacY activity. (454 aa)    
Predicted Functional Partners:
ptsG
PTS system glucose-specific EIICBA component.
 0.999
glcB
PTS system glucoside-specific EIICBA component.
 
 0.996
sacA
Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
 
 
 0.965
bglK
Beta-glucoside kinase.
  
 0.951
glcK
Glucokinase.
  
 0.951
pagL
Phospho-alpha-glucosidase PagL.
 
 
 0.860
adhE
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
     
 0.854
sacY
Levansucrase and sucrase synthesis operon antiterminator.
 
 0.844
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
  
 
 0.833
fruA_2
PTS system fructose-specific EIIBC component.
   
  
 0.820
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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