Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
pagLPhospho-alpha-glucosidase PagL. (440 aa)    
Predicted Functional Partners:
glcB
PTS system glucoside-specific EIICBA component.
 
 
 0.973
ptsG
PTS system glucose-specific EIICBA component.
 
 
 0.971
malX_1
PTS system maltose- and glucose-specific EIICB component.
 
 
 0.945
licC
Lichenan permease IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
 
 
 0.929
licB
Lichenan-specific phosphotransferase enzyme IIB component.
 
 
 0.923
lacF_2
Lactose-specific phosphotransferase enzyme IIA component.
 
 
 0.911
treB
PTS system trehalose-specific EIIBC component.
 
 
 0.907
sacX_2
Negative regulator of SacY activity.
 
 
 0.880
sacX_1
Negative regulator of SacY activity.
 
 
 0.871
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
     
 0.810
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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