trxA_1 protein (Clostridium thermoalcaliphilum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

trxA_1

Thioredoxin; Belongs to the thioredoxin family. (105 aa)

Predicted Functional Partners:

trxB_1

0.984

trxB_2

0.932

gap

0.812

fusA_1

0.805

thrZ_2

0.804

fusA_2

0.803

groL

0.788

ribBA

0.752

OPJ56036.1

0.720

dnaK

0.636

Your Current Organism:

Clostridium thermoalcaliphilum

NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OPJ56036.1	dnaK	CLOTH_12140	CLOTH_13620	Blue-light-activated protein.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.631
OPJ56036.1	fusA_1	CLOTH_12140	CLOTH_18620	Blue-light-activated protein.	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.407
OPJ56036.1	fusA_2	CLOTH_12140	CLOTH_19000	Blue-light-activated protein.	Elongation factor G.	0.407
OPJ56036.1	gap	CLOTH_12140	CLOTH_08360	Blue-light-activated protein.	Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.477
OPJ56036.1	groL	CLOTH_12140	CLOTH_11760	Blue-light-activated protein.	60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.636
OPJ56036.1	ribBA	CLOTH_12140	CLOTH_14300	Blue-light-activated protein.	Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.	0.953
OPJ56036.1	thrZ_2	CLOTH_12140	CLOTH_09810	Blue-light-activated protein.	threonine--tRNA ligase 2.	0.464
OPJ56036.1	trxA_1	CLOTH_12140	CLOTH_05300	Blue-light-activated protein.	Thioredoxin; Belongs to the thioredoxin family.	0.720
OPJ56036.1	trxB_1	CLOTH_12140	CLOTH_05290	Blue-light-activated protein.	Thioredoxin reductase.	0.686
OPJ56036.1	trxB_2	CLOTH_12140	CLOTH_09580	Blue-light-activated protein.	Thioredoxin reductase.	0.701
dnaK	OPJ56036.1	CLOTH_13620	CLOTH_12140	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Blue-light-activated protein.	0.631
dnaK	fusA_1	CLOTH_13620	CLOTH_18620	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.842
dnaK	fusA_2	CLOTH_13620	CLOTH_19000	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Elongation factor G.	0.762
dnaK	gap	CLOTH_13620	CLOTH_08360	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.798
dnaK	groL	CLOTH_13620	CLOTH_11760	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.994
dnaK	thrZ_2	CLOTH_13620	CLOTH_09810	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	threonine--tRNA ligase 2.	0.656
dnaK	trxA_1	CLOTH_13620	CLOTH_05300	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Thioredoxin; Belongs to the thioredoxin family.	0.636
fusA_1	OPJ56036.1	CLOTH_18620	CLOTH_12140	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Blue-light-activated protein.	0.407
fusA_1	dnaK	CLOTH_18620	CLOTH_13620	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.842
fusA_1	gap	CLOTH_18620	CLOTH_08360	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.476