fur protein (Clostridium thermoalcaliphilum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

fur

Ferric uptake regulation protein; Belongs to the Fur family. (144 aa)

Predicted Functional Partners:

rpoA

0.795

OPJ57283.1

0.789

sigA

0.778

rpoB

0.752

purL

0.705

tsaA

0.697

rpoC

0.697

rpoZ

0.696

znuC

0.670

prxU

0.661

Your Current Organism:

Clostridium thermoalcaliphilum

NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OPJ57283.1	fur	CLOTH_05660	CLOTH_05650	Hypothetical protein; Belongs to the UPF0473 family.	Ferric uptake regulation protein; Belongs to the Fur family.	0.789
fur	OPJ57283.1	CLOTH_05650	CLOTH_05660	Ferric uptake regulation protein; Belongs to the Fur family.	Hypothetical protein; Belongs to the UPF0473 family.	0.789
fur	prxU	CLOTH_05650	CLOTH_16440	Ferric uptake regulation protein; Belongs to the Fur family.	Selenocysteine-containing peroxiredoxin PrxU; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	0.661
fur	purL	CLOTH_05650	CLOTH_11620	Ferric uptake regulation protein; Belongs to the Fur family.	Phosphoribosylformylglycinamidine synthase 2.	0.705
fur	rpoA	CLOTH_05650	CLOTH_18300	Ferric uptake regulation protein; Belongs to the Fur family.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.795
fur	rpoB	CLOTH_05650	CLOTH_18670	Ferric uptake regulation protein; Belongs to the Fur family.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.752
fur	rpoC	CLOTH_05650	CLOTH_18660	Ferric uptake regulation protein; Belongs to the Fur family.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.697
fur	rpoZ	CLOTH_05650	CLOTH_01840	Ferric uptake regulation protein; Belongs to the Fur family.	DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.696
fur	sigA	CLOTH_05650	CLOTH_03350	Ferric uptake regulation protein; Belongs to the Fur family.	RNA polymerase sigma factor SigA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.778
fur	tsaA	CLOTH_05650	CLOTH_01020	Ferric uptake regulation protein; Belongs to the Fur family.	Putative peroxiredoxin.	0.697
fur	znuC	CLOTH_05650	CLOTH_07810	Ferric uptake regulation protein; Belongs to the Fur family.	High-affinity zinc uptake system ATP-binding protein ZnuC.	0.670
prxU	fur	CLOTH_16440	CLOTH_05650	Selenocysteine-containing peroxiredoxin PrxU; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	Ferric uptake regulation protein; Belongs to the Fur family.	0.661
prxU	sigA	CLOTH_16440	CLOTH_03350	Selenocysteine-containing peroxiredoxin PrxU; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	RNA polymerase sigma factor SigA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.533
purL	fur	CLOTH_11620	CLOTH_05650	Phosphoribosylformylglycinamidine synthase 2.	Ferric uptake regulation protein; Belongs to the Fur family.	0.705
purL	rpoA	CLOTH_11620	CLOTH_18300	Phosphoribosylformylglycinamidine synthase 2.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.543
purL	rpoB	CLOTH_11620	CLOTH_18670	Phosphoribosylformylglycinamidine synthase 2.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.784
rpoA	fur	CLOTH_18300	CLOTH_05650	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Ferric uptake regulation protein; Belongs to the Fur family.	0.795
rpoA	purL	CLOTH_18300	CLOTH_11620	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Phosphoribosylformylglycinamidine synthase 2.	0.543
rpoA	rpoB	CLOTH_18300	CLOTH_18670	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
rpoA	rpoC	CLOTH_18300	CLOTH_18660	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999