iscU protein (Clostridium thermoalcaliphilum)

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second shell of interactors

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Score

iscU

Iron-sulfur cluster assembly scaffold protein IscU. (145 aa)

Predicted Functional Partners:

iscS_1

0.998

iscS_2

0.994

csd_1

0.970

csd_2

0.970

cymR

0.950

OPJ54735.1

0.903

dnaK

0.890

mnmA

0.769

nifJ

0.694

OPJ57096.1

0.568

Your Current Organism:

Clostridium thermoalcaliphilum

NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OPJ54735.1	iscU	CLOTH_19560	CLOTH_05740	Hypothetical protein.	Iron-sulfur cluster assembly scaffold protein IscU.	0.903
OPJ54735.1	nifJ	CLOTH_19560	CLOTH_01250	Hypothetical protein.	Pyruvate-flavodoxin oxidoreductase.	0.527
OPJ57096.1	iscU	CLOTH_03790	CLOTH_05740	Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.	Iron-sulfur cluster assembly scaffold protein IscU.	0.568
csd_1	iscU	CLOTH_14060	CLOTH_05740	Putative cysteine desulfurase.	Iron-sulfur cluster assembly scaffold protein IscU.	0.970
csd_1	nifJ	CLOTH_14060	CLOTH_01250	Putative cysteine desulfurase.	Pyruvate-flavodoxin oxidoreductase.	0.602
csd_2	iscU	CLOTH_15080	CLOTH_05740	Putative cysteine desulfurase.	Iron-sulfur cluster assembly scaffold protein IscU.	0.970
csd_2	nifJ	CLOTH_15080	CLOTH_01250	Putative cysteine desulfurase.	Pyruvate-flavodoxin oxidoreductase.	0.602
cymR	iscS_1	CLOTH_05760	CLOTH_05750	HTH-type transcriptional regulator CymR.	Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.	0.954
cymR	iscS_2	CLOTH_05760	CLOTH_16380	HTH-type transcriptional regulator CymR.	Cysteine desulfurase IscS.	0.817
cymR	iscU	CLOTH_05760	CLOTH_05740	HTH-type transcriptional regulator CymR.	Iron-sulfur cluster assembly scaffold protein IscU.	0.950
cymR	mnmA	CLOTH_05760	CLOTH_05730	HTH-type transcriptional regulator CymR.	tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.	0.660
cymR	nifJ	CLOTH_05760	CLOTH_01250	HTH-type transcriptional regulator CymR.	Pyruvate-flavodoxin oxidoreductase.	0.641
dnaK	iscS_1	CLOTH_13620	CLOTH_05750	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.	0.588
dnaK	iscS_2	CLOTH_13620	CLOTH_16380	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Cysteine desulfurase IscS.	0.617
dnaK	iscU	CLOTH_13620	CLOTH_05740	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Iron-sulfur cluster assembly scaffold protein IscU.	0.890
dnaK	mnmA	CLOTH_13620	CLOTH_05730	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.	0.493
dnaK	nifJ	CLOTH_13620	CLOTH_01250	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Pyruvate-flavodoxin oxidoreductase.	0.527
iscS_1	cymR	CLOTH_05750	CLOTH_05760	Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.	HTH-type transcriptional regulator CymR.	0.954
iscS_1	dnaK	CLOTH_05750	CLOTH_13620	Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.588
iscS_1	iscU	CLOTH_05750	CLOTH_05740	Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.	Iron-sulfur cluster assembly scaffold protein IscU.	0.998