| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cfiB | cymR | CLOTH_05770 | CLOTH_05760 | 2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | HTH-type transcriptional regulator CymR. | 0.470 |
| cfiB | iscS_1 | CLOTH_05770 | CLOTH_05750 | 2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.488 |
| cfiB | iscU | CLOTH_05770 | CLOTH_05740 | 2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Iron-sulfur cluster assembly scaffold protein IscU. | 0.441 |
| cfiB | nifJ | CLOTH_05770 | CLOTH_01250 | 2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Pyruvate-flavodoxin oxidoreductase. | 0.949 |
| cymR | cfiB | CLOTH_05760 | CLOTH_05770 | HTH-type transcriptional regulator CymR. | 2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.470 |
| cymR | fliG | CLOTH_05760 | CLOTH_03670 | HTH-type transcriptional regulator CymR. | Flagellar motor switch protein FliG. | 0.519 |
| cymR | fur | CLOTH_05760 | CLOTH_05650 | HTH-type transcriptional regulator CymR. | Ferric uptake regulation protein; Belongs to the Fur family. | 0.406 |
| cymR | iscS_1 | CLOTH_05760 | CLOTH_05750 | HTH-type transcriptional regulator CymR. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.954 |
| cymR | iscS_2 | CLOTH_05760 | CLOTH_16380 | HTH-type transcriptional regulator CymR. | Cysteine desulfurase IscS. | 0.817 |
| cymR | iscU | CLOTH_05760 | CLOTH_05740 | HTH-type transcriptional regulator CymR. | Iron-sulfur cluster assembly scaffold protein IscU. | 0.950 |
| cymR | mnmA | CLOTH_05760 | CLOTH_05730 | HTH-type transcriptional regulator CymR. | tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.660 |
| cymR | nifJ | CLOTH_05760 | CLOTH_01250 | HTH-type transcriptional regulator CymR. | Pyruvate-flavodoxin oxidoreductase. | 0.641 |
| fliG | cymR | CLOTH_03670 | CLOTH_05760 | Flagellar motor switch protein FliG. | HTH-type transcriptional regulator CymR. | 0.519 |
| fur | cymR | CLOTH_05650 | CLOTH_05760 | Ferric uptake regulation protein; Belongs to the Fur family. | HTH-type transcriptional regulator CymR. | 0.406 |
| iscS_1 | cfiB | CLOTH_05750 | CLOTH_05770 | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.488 |
| iscS_1 | cymR | CLOTH_05750 | CLOTH_05760 | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | HTH-type transcriptional regulator CymR. | 0.954 |
| iscS_1 | iscU | CLOTH_05750 | CLOTH_05740 | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | Iron-sulfur cluster assembly scaffold protein IscU. | 0.998 |
| iscS_1 | mnmA | CLOTH_05750 | CLOTH_05730 | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.787 |
| iscS_2 | cymR | CLOTH_16380 | CLOTH_05760 | Cysteine desulfurase IscS. | HTH-type transcriptional regulator CymR. | 0.817 |
| iscS_2 | iscU | CLOTH_16380 | CLOTH_05740 | Cysteine desulfurase IscS. | Iron-sulfur cluster assembly scaffold protein IscU. | 0.994 |