Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)    
Predicted Functional Partners:
OPJ56409.1
Proline racemase; Belongs to the proline racemase family.
    
 0.940
OPJ57296.1
Hypothetical protein; Alanine racemase, N-terminal domain.
     
  0.762
adhE
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.720
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.712
OPJ56792.1
Hypothetical protein; Alanine racemase, N-terminal domain.
     
  0.691
pflB
Formate acetyltransferase.
    
 0.683
OPJ55157.1
Aspartate racemase.
     
  0.634
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.589
purL
Phosphoribosylformylglycinamidine synthase 2.
     
 0.569
OPJ56880.1
Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
 
  
 0.546
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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