Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mdeAMethionine gamma-lyase. (397 aa)    
Predicted Functional Partners:
cysK
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.984
nifJ
Pyruvate-flavodoxin oxidoreductase.
    
 0.923
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
 
 0.908
metK_2
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
 0.904
trpB
Tryptophan synthase beta chain.
  
 0.879
trxB_2
Thioredoxin reductase.
   
 
 0.871
cysE_1
Serine acetyltransferase.
  
 
 0.864
trxB_1
Thioredoxin reductase.
   
 
 0.846
cdr
Coenzyme A disulfide reductase.
  
 
 0.841
glpE
Thiosulfate sulfurtransferase GlpE.
  
 
 0.841
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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