Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (676 aa)    
Predicted Functional Partners:
hutH
Histidine ammonia-lyase.
 
 0.999
hutI
Imidazolonepropionase.
 
 
 0.999
OPJ56505.1
Hypothetical protein; Formiminotransferase domain, N-terminal subdomain.
 
    0.926
fchA
Methenyltetrahydrofolate cyclohydrolase.
 
     0.851
pyrC_2
Dihydroorotase.
  
 
 0.838
speB
Agmatinase; Belongs to the arginase family.
  
  
 0.477
rocF
Arginase; Belongs to the arginase family.
  
  
 0.477
ccpA
Catabolite control protein A.
       0.465
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
Server load: low (20%) [HD]