Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
wbpAUDP-N-acetyl-D-glucosamine 6-dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (442 aa)    
Predicted Functional Partners:
mnaA
UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
 
 0.985
pglF
UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase.
 
 
 0.877
murG_2
UDP-N-acetylglucosamine transferase.
 
     0.821
glmU
Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
  
 
 0.818
epsN
Putative pyridoxal phosphate-dependent aminotransferase EpsN; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.809
OPJ55134.1
Putative epimerase/dehydratase.
  
 
 0.763
OPJ56510.1
Hypothetical protein.
 
     0.749
pglC
Undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase.
  
 
 0.640
tagO
Putative undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase.
  
 
 0.593
OPJ55312.1
Polysaccharide biosynthesis protein.
  
  
 0.590
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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