acrA protein (Clostridium thermoalcaliphilum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

acrA

acryloyl-CoA reductase electron transfer subunit beta. (333 aa)

Predicted Functional Partners:

acrB

0.999

acdA

0.998

pyk

0.960

nifJ

0.945

echA8

0.909

mmgB

0.897

thlA

0.866

accB

0.865

hndA_1

0.829

hndC_1

0.813

Your Current Organism:

Clostridium thermoalcaliphilum

NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
accB	acdA	CLOTH_04800	CLOTH_09370	Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	acyl-CoA dehydrogenase.	0.902
accB	acrA	CLOTH_04800	CLOTH_09350	Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	acryloyl-CoA reductase electron transfer subunit beta.	0.865
accB	acrB	CLOTH_04800	CLOTH_09360	Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	acryloyl-CoA reductase electron transfer subunit gamma.	0.865
accB	echA8	CLOTH_04800	CLOTH_13040	Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	Putative enoyl-CoA hydratase echA8; Belongs to the enoyl-CoA hydratase/isomerase family.	0.938
accB	hndA_1	CLOTH_04800	CLOTH_04650	Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	NADP-reducing hydrogenase subunit HndA.	0.878
accB	hndC_1	CLOTH_04800	CLOTH_04660	Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	NADP-reducing hydrogenase subunit HndC.	0.875
accB	mmgB	CLOTH_04800	CLOTH_13050	Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	Putative 3-hydroxybutyryl-CoA dehydrogenase.	0.829
accB	nifJ	CLOTH_04800	CLOTH_01250	Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	Pyruvate-flavodoxin oxidoreductase.	0.967
accB	pyk	CLOTH_04800	CLOTH_18010	Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.954
accB	thlA	CLOTH_04800	CLOTH_09380	Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.910
acdA	accB	CLOTH_09370	CLOTH_04800	acyl-CoA dehydrogenase.	Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.902
acdA	acrA	CLOTH_09370	CLOTH_09350	acyl-CoA dehydrogenase.	acryloyl-CoA reductase electron transfer subunit beta.	0.998
acdA	acrB	CLOTH_09370	CLOTH_09360	acyl-CoA dehydrogenase.	acryloyl-CoA reductase electron transfer subunit gamma.	0.998
acdA	echA8	CLOTH_09370	CLOTH_13040	acyl-CoA dehydrogenase.	Putative enoyl-CoA hydratase echA8; Belongs to the enoyl-CoA hydratase/isomerase family.	0.998
acdA	hndA_1	CLOTH_09370	CLOTH_04650	acyl-CoA dehydrogenase.	NADP-reducing hydrogenase subunit HndA.	0.898
acdA	hndC_1	CLOTH_09370	CLOTH_04660	acyl-CoA dehydrogenase.	NADP-reducing hydrogenase subunit HndC.	0.833
acdA	mmgB	CLOTH_09370	CLOTH_13050	acyl-CoA dehydrogenase.	Putative 3-hydroxybutyryl-CoA dehydrogenase.	0.987
acdA	nifJ	CLOTH_09370	CLOTH_01250	acyl-CoA dehydrogenase.	Pyruvate-flavodoxin oxidoreductase.	0.954
acdA	thlA	CLOTH_09370	CLOTH_09380	acyl-CoA dehydrogenase.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.996
acrA	accB	CLOTH_09350	CLOTH_04800	acryloyl-CoA reductase electron transfer subunit beta.	Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.865