Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tmpCMembrane lipoprotein TmpC precursor. (341 aa)    
Predicted Functional Partners:
mglA_2
Galactose/methyl galactoside import ATP-binding protein MglA.
 
 
 0.995
rbsC_2
Ribose transport system permease protein RbsC; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.992
OPJ55769.1
Ribose ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.987
mglA_1
Galactose/methyl galactoside import ATP-binding protein MglA.
 
  
  0.718
rbsA
Ribose import ATP-binding protein RbsA; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
 
  
  0.633
spoIIGA
Sporulation sigma-E factor-processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
   
    0.574
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.561
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.488
grdD
Glycine/sarcosine/betaine reductase complex component C subunit alpha; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
     
 0.465
pdp
Pyrimidine-nucleoside phosphorylase.
     
 0.459
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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