node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OPJ55792.1 | cobS | CLOTH_09700 | CLOTH_09670 | Hypothetical protein. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.723 |
OPJ55792.1 | cobU | CLOTH_09700 | CLOTH_09680 | Hypothetical protein. | Bifunctional adenosylcobalamin biosynthesis protein CobU. | 0.771 |
OPJ55792.1 | ogt | CLOTH_09700 | CLOTH_09690 | Hypothetical protein. | methylated-DNA--protein-cysteine methyltransferase, constitutive; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.812 |
OPJ55792.1 | pspA_2 | CLOTH_09700 | CLOTH_09660 | Hypothetical protein. | Phosphoserine phosphatase 1. | 0.703 |
OPJ55792.1 | ywpJ | CLOTH_09700 | CLOTH_09650 | Hypothetical protein. | Putative phosphatase YwpJ. | 0.746 |
cbiB | cobQ | CLOTH_11540 | CLOTH_20350 | Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.991 |
cbiB | cobS | CLOTH_11540 | CLOTH_09670 | Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.899 |
cbiB | cobT | CLOTH_11540 | CLOTH_11800 | Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.899 |
cbiB | cobU | CLOTH_11540 | CLOTH_09680 | Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Bifunctional adenosylcobalamin biosynthesis protein CobU. | 0.995 |
cbiB | nasF | CLOTH_11540 | CLOTH_11460 | Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | uroporphyrinogen-III C-methyltransferase. | 0.910 |
cbiB | pspA_2 | CLOTH_11540 | CLOTH_09660 | Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Phosphoserine phosphatase 1. | 0.553 |
cbiB | yvqK | CLOTH_11540 | CLOTH_01110 | Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.875 |
cobQ | cbiB | CLOTH_20350 | CLOTH_11540 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.991 |
cobQ | cobS | CLOTH_20350 | CLOTH_09670 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.930 |
cobQ | cobT | CLOTH_20350 | CLOTH_11800 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.912 |
cobQ | cobU | CLOTH_20350 | CLOTH_09680 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Bifunctional adenosylcobalamin biosynthesis protein CobU. | 0.983 |
cobQ | nasF | CLOTH_20350 | CLOTH_11460 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | uroporphyrinogen-III C-methyltransferase. | 0.829 |
cobQ | pspA_2 | CLOTH_20350 | CLOTH_09660 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Phosphoserine phosphatase 1. | 0.617 |
cobQ | yvqK | CLOTH_20350 | CLOTH_01110 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.936 |
cobS | OPJ55792.1 | CLOTH_09670 | CLOTH_09700 | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Hypothetical protein. | 0.723 |