Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hrp1Hypoxic response protein 1. (137 aa)    
Predicted Functional Partners:
nifJ
Pyruvate-flavodoxin oxidoreductase.
    
  0.910
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.896
thrZ_2
threonine--tRNA ligase 2.
    
 0.809
spsB
Signal peptidase IB; Belongs to the peptidase S26 family.
       0.684
OPJ55807.1
Hypothetical protein.
  
    0.682
nfo_2
Endonuclease 4.
       0.679
glsA2
Glutaminase 2; Belongs to the glutaminase family.
       0.568
yqfL
Putative pyruvate, phosphate dikinase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
 
  
 0.490
OPJ56429.1
Chlorophenol reductase precursor.
  
   
 0.478
OPJ55808.1
YceG-like family protein.
       0.454
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.