Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
xylAXylose isomerase; Belongs to the xylose isomerase family. (444 aa)    
Predicted Functional Partners:
xylB
Xylulose kinase.
 
 
 0.995
xynB
Beta-xylosidase; Belongs to the glycosyl hydrolase 43 family.
 
 
 0.987
fruA_2
PTS system fructose-specific EIIBC component.
     
 0.930
glcK
Glucokinase.
    
 0.738
iolC
5-dehydro-2-deoxygluconokinase; Belongs to the carbohydrate kinase PfkB family.
    
 0.733
OPJ55844.1
Hypothetical protein.
 
     0.684
fruA_1
PTS system fructose-specific EIIABC component.
     
 0.662
msmE
Multiple sugar-binding protein precursor.
 
   
 0.649
sacA
Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
     
 0.643
bglC
aryl-phospho-beta-D-glucosidase BglC; Belongs to the glycosyl hydrolase 1 family.
    
 0.594
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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