Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pchRRegulatory protein PchR. (332 aa)    
Predicted Functional Partners:
nifJ
Pyruvate-flavodoxin oxidoreductase.
     
 0.904
yfiY
Putative siderophore-binding lipoprotein YfiY precursor.
 
  
 0.883
ribBA
Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.872
OPJ55853.1
2-acyl-glycerophospho-ethanolamine acyltransferase.
 
     0.831
ypdA_2
Sensor histidine kinase YpdA.
 
  
 0.818
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.804
yfhA
Putative siderophore transport system permease protein YfhA; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.774
feuB
Iron-uptake system permease protein FeuB; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.770
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.764
yusV_1
Putative siderophore transport system ATP-binding protein YusV.
 
  
 0.744
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.