STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fokIM_1Modification methylase FokI. (644 aa)    
Predicted Functional Partners:
dpnA
Modification methylase DpnIIB; Belongs to the N(4)/N(6)-methyltransferase family.
  
  
 0.755
parB_1
Putative chromosome-partitioning protein ParB; Belongs to the N(4)/N(6)-methyltransferase family.
  
  
 0.755
fokIR
Type-2 restriction enzyme FokI.
       0.741
hhaIM
Modification methylase HhaI; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
     
 0.715
OPJ55922.1
Transposase DDE domain protein.
       0.629
OPJ55919.1
RNA polymerase sigma factor SigD; Belongs to the sigma-70 factor family. ECF subfamily.
  
    0.512
OPJ55648.1
Hypothetical protein.
   
 
 0.467
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
      
 0.465
OPJ55917.1
Hypothetical protein.
       0.449
OPJ55005.1
Phage antirepressor protein KilAC domain protein.
       0.429
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.