| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OPJ55948.1 | guaA | CLOTH_11260 | CLOTH_11700 | Cobalt-dependent inorganic pyrophosphatase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.985 |
| OPJ55948.1 | guaB | CLOTH_11260 | CLOTH_11710 | Cobalt-dependent inorganic pyrophosphatase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.891 |
| OPJ55948.1 | pheT | CLOTH_11260 | CLOTH_16780 | Cobalt-dependent inorganic pyrophosphatase. | phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.644 |
| OPJ55948.1 | purA | CLOTH_11260 | CLOTH_14890 | Cobalt-dependent inorganic pyrophosphatase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.890 |
| OPJ55948.1 | purH | CLOTH_11260 | CLOTH_11640 | Cobalt-dependent inorganic pyrophosphatase. | Bifunctional purine biosynthesis protein PurH. | 0.793 |
| OPJ55948.1 | purL | CLOTH_11260 | CLOTH_11620 | Cobalt-dependent inorganic pyrophosphatase. | Phosphoribosylformylglycinamidine synthase 2. | 0.734 |
| OPJ55948.1 | rph | CLOTH_11260 | CLOTH_07120 | Cobalt-dependent inorganic pyrophosphatase. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.944 |
| OPJ55948.1 | surE | CLOTH_11260 | CLOTH_04920 | Cobalt-dependent inorganic pyrophosphatase. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.796 |
| guaA | OPJ55948.1 | CLOTH_11700 | CLOTH_11260 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Cobalt-dependent inorganic pyrophosphatase. | 0.985 |
| guaA | guaB | CLOTH_11700 | CLOTH_11710 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA | pheT | CLOTH_11700 | CLOTH_16780 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.957 |
| guaA | purA | CLOTH_11700 | CLOTH_14890 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.967 |
| guaA | purF | CLOTH_11700 | CLOTH_11670 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.921 |
| guaA | purH | CLOTH_11700 | CLOTH_11640 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Bifunctional purine biosynthesis protein PurH. | 0.961 |
| guaA | purL | CLOTH_11700 | CLOTH_11620 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase 2. | 0.999 |
| guaA | ribBA | CLOTH_11700 | CLOTH_14300 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.845 |
| guaA | rph | CLOTH_11700 | CLOTH_07120 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.985 |
| guaA | surE | CLOTH_11700 | CLOTH_04920 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.976 |
| guaB | OPJ55948.1 | CLOTH_11710 | CLOTH_11260 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Cobalt-dependent inorganic pyrophosphatase. | 0.891 |
| guaB | guaA | CLOTH_11710 | CLOTH_11700 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
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