node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
carA | carB | CLOTH_11420 | CLOTH_11410 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Carbamoyl-phosphate synthase large chain. | 0.999 |
carA | pyrB | CLOTH_11420 | CLOTH_11910 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Aspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC_1 | CLOTH_11420 | CLOTH_11890 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.997 |
carA | pyrD | CLOTH_11420 | CLOTH_11860 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotate dehydrogenase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. | 0.929 |
carA | pyrE | CLOTH_11420 | CLOTH_11850 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.951 |
carA | pyrF | CLOTH_11420 | CLOTH_11880 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.960 |
carA | pyrI | CLOTH_11420 | CLOTH_11900 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Aspartate carbamoyltransferase regulatory chain. | 0.858 |
carA | pyrK_2 | CLOTH_11420 | CLOTH_11870 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotate dehydrogenase B, electron transfer subunit. | 0.863 |
carA | pyrR | CLOTH_11420 | CLOTH_01760 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.839 |
carA | uraA | CLOTH_11420 | CLOTH_01770 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Uracil permease. | 0.836 |
carB | carA | CLOTH_11410 | CLOTH_11420 | Carbamoyl-phosphate synthase large chain. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.999 |
carB | pyrB | CLOTH_11410 | CLOTH_11910 | Carbamoyl-phosphate synthase large chain. | Aspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carB | pyrC_1 | CLOTH_11410 | CLOTH_11890 | Carbamoyl-phosphate synthase large chain. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.996 |
carB | pyrD | CLOTH_11410 | CLOTH_11860 | Carbamoyl-phosphate synthase large chain. | Dihydroorotate dehydrogenase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. | 0.987 |
carB | pyrE | CLOTH_11410 | CLOTH_11850 | Carbamoyl-phosphate synthase large chain. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.969 |
carB | pyrF | CLOTH_11410 | CLOTH_11880 | Carbamoyl-phosphate synthase large chain. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.967 |
carB | pyrI | CLOTH_11410 | CLOTH_11900 | Carbamoyl-phosphate synthase large chain. | Aspartate carbamoyltransferase regulatory chain. | 0.945 |
carB | pyrK_2 | CLOTH_11410 | CLOTH_11870 | Carbamoyl-phosphate synthase large chain. | Dihydroorotate dehydrogenase B, electron transfer subunit. | 0.869 |
carB | pyrR | CLOTH_11410 | CLOTH_01760 | Carbamoyl-phosphate synthase large chain. | Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.897 |
carB | uraA | CLOTH_11410 | CLOTH_01770 | Carbamoyl-phosphate synthase large chain. | Uracil permease. | 0.821 |