Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
rexRedox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (212 aa)    
Predicted Functional Partners:
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
   
    0.907
adhE
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.743
acdA
acyl-CoA dehydrogenase.
     
 0.665
mmgB
Putative 3-hydroxybutyryl-CoA dehydrogenase.
     
 0.645
hndA_1
NADP-reducing hydrogenase subunit HndA.
 
  
 0.635
rpsP
30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
   
    0.587
carD
RNA polymerase-binding transcription factor CarD.
   
    0.560
echA8
Putative enoyl-CoA hydratase echA8; Belongs to the enoyl-CoA hydratase/isomerase family.
     
 0.538
nifJ
Pyruvate-flavodoxin oxidoreductase.
      
 0.533
nasF
uroporphyrinogen-III C-methyltransferase.
 
     0.526
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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