Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
degSSignal transduction histidine-protein kinase/phosphatase DegS. (386 aa)    
Predicted Functional Partners:
degU
Transcriptional regulatory protein DegU.
 
 0.999
OPJ56036.1
Blue-light-activated protein.
   
 0.918
kinE
Sporulation kinase E.
  
 0.854
OPJ56057.1
Hypothetical protein.
  
     0.627
apeA
Putative M18 family aminopeptidase 1.
       0.573
kinA
Sporulation kinase A.
  
 0.573
prkC
Serine/threonine-protein kinase PrkC.
 
  
 0.558
ycgR
Flagellar brake protein YcgR.
 
    0.555
gmr
Cyclic di-GMP phosphodiesterase Gmr.
   
 0.543
OPJ55256.1
Hypothetical protein.
  
     0.536
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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