tdcB protein (Clostridium thermoalcaliphilum)

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Score

tdcB

L-threonine dehydratase catabolic TdcB. (407 aa)

Predicted Functional Partners:

nifJ

0.951

sdhA

0.927

sdhB

0.896

glyA

0.890

pspA_1

0.879

cysE_1

0.872

pflB

0.870

gloA_1

0.869

ltaA

0.813

yabJ

0.812

Your Current Organism:

Clostridium thermoalcaliphilum

NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cysE_1	glyA	CLOTH_18830	CLOTH_00660	Serine acetyltransferase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.903
cysE_1	nifJ	CLOTH_18830	CLOTH_01250	Serine acetyltransferase.	Pyruvate-flavodoxin oxidoreductase.	0.552
cysE_1	pspA_1	CLOTH_18830	CLOTH_04860	Serine acetyltransferase.	Phosphoserine phosphatase 1; Belongs to the phosphoglycerate mutase family.	0.857
cysE_1	sdhA	CLOTH_18830	CLOTH_13300	Serine acetyltransferase.	L-serine dehydratase, alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.874
cysE_1	sdhB	CLOTH_18830	CLOTH_13290	Serine acetyltransferase.	L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.874
cysE_1	tdcB	CLOTH_18830	CLOTH_13270	Serine acetyltransferase.	L-threonine dehydratase catabolic TdcB.	0.872
gloA_1	nifJ	CLOTH_06660	CLOTH_01250	Lactoylglutathione lyase.	Pyruvate-flavodoxin oxidoreductase.	0.934
gloA_1	sdhA	CLOTH_06660	CLOTH_13300	Lactoylglutathione lyase.	L-serine dehydratase, alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.867
gloA_1	sdhB	CLOTH_06660	CLOTH_13290	Lactoylglutathione lyase.	L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.795
gloA_1	tdcB	CLOTH_06660	CLOTH_13270	Lactoylglutathione lyase.	L-threonine dehydratase catabolic TdcB.	0.869
glyA	cysE_1	CLOTH_00660	CLOTH_18830	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Serine acetyltransferase.	0.903
glyA	ltaA	CLOTH_00660	CLOTH_01140	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	L-allo-threonine aldolase.	0.817
glyA	nifJ	CLOTH_00660	CLOTH_01250	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Pyruvate-flavodoxin oxidoreductase.	0.744
glyA	pspA_1	CLOTH_00660	CLOTH_04860	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Phosphoserine phosphatase 1; Belongs to the phosphoglycerate mutase family.	0.885
glyA	sdhA	CLOTH_00660	CLOTH_13300	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	L-serine dehydratase, alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.961
glyA	sdhB	CLOTH_00660	CLOTH_13290	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.961
glyA	tdcB	CLOTH_00660	CLOTH_13270	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	L-threonine dehydratase catabolic TdcB.	0.890
ltaA	glyA	CLOTH_01140	CLOTH_00660	L-allo-threonine aldolase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.817
ltaA	tdcB	CLOTH_01140	CLOTH_13270	L-allo-threonine aldolase.	L-threonine dehydratase catabolic TdcB.	0.813
nifJ	cysE_1	CLOTH_01250	CLOTH_18830	Pyruvate-flavodoxin oxidoreductase.	Serine acetyltransferase.	0.552