| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| adhE | guaA | CLOTH_11210 | CLOTH_11700 | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.805 |
| adhE | rph | CLOTH_11210 | CLOTH_07120 | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.466 |
| adhE | sdhA | CLOTH_11210 | CLOTH_13300 | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | L-serine dehydratase, alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.529 |
| adhE | sdhB | CLOTH_11210 | CLOTH_13290 | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.529 |
| adhE | tdcB | CLOTH_11210 | CLOTH_13270 | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | L-threonine dehydratase catabolic TdcB. | 0.653 |
| adhE | yabJ | CLOTH_11210 | CLOTH_13280 | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 2-iminobutanoate/2-iminopropanoate deaminase. | 0.751 |
| apt | guaA | CLOTH_00540 | CLOTH_11700 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.990 |
| apt | rph | CLOTH_00540 | CLOTH_07120 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.769 |
| apt | yabJ | CLOTH_00540 | CLOTH_13280 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 2-iminobutanoate/2-iminopropanoate deaminase. | 0.803 |
| fusA_1 | guaA | CLOTH_18620 | CLOTH_11700 | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.757 |
| fusA_1 | yabJ | CLOTH_18620 | CLOTH_13280 | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | 2-iminobutanoate/2-iminopropanoate deaminase. | 0.876 |
| fusA_2 | guaA | CLOTH_19000 | CLOTH_11700 | Elongation factor G. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.757 |
| fusA_2 | yabJ | CLOTH_19000 | CLOTH_13280 | Elongation factor G. | 2-iminobutanoate/2-iminopropanoate deaminase. | 0.876 |
| guaA | adhE | CLOTH_11700 | CLOTH_11210 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.805 |
| guaA | apt | CLOTH_11700 | CLOTH_00540 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.990 |
| guaA | fusA_1 | CLOTH_11700 | CLOTH_18620 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | 0.757 |
| guaA | fusA_2 | CLOTH_11700 | CLOTH_19000 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Elongation factor G. | 0.757 |
| guaA | rph | CLOTH_11700 | CLOTH_07120 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.985 |
| guaA | tdcB | CLOTH_11700 | CLOTH_13270 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | L-threonine dehydratase catabolic TdcB. | 0.495 |
| guaA | yabJ | CLOTH_11700 | CLOTH_13280 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 2-iminobutanoate/2-iminopropanoate deaminase. | 0.648 |