STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OPJ55615.1NAD-dependent malic enzyme. (391 aa)    
Predicted Functional Partners:
fumB
Fumarate hydratase class I, anaerobic.
 
 
 0.995
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.984
ttdA
L(+)-tartrate dehydratase subunit alpha.
  
 
 0.980
nifJ
Pyruvate-flavodoxin oxidoreductase.
    
 0.967
cfiB
2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.955
hndA_1
NADP-reducing hydrogenase subunit HndA.
    
 0.943
ppdK
Pyruvate, phosphate dikinase.
   
 
 0.916
pflB
Formate acetyltransferase.
   
 
 0.915
korA_2
2-oxoglutarate oxidoreductase subunit KorA.
     
 0.897
korB_2
2-oxoglutarate oxidoreductase subunit KorB.
     
 0.897
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
Server load: low (18%) [HD]