Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
lacF_2Lactose-specific phosphotransferase enzyme IIA component. (108 aa)    
Predicted Functional Partners:
licB
Lichenan-specific phosphotransferase enzyme IIB component.
 
 0.999
licC
Lichenan permease IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
 
 
 0.998
bglC
aryl-phospho-beta-D-glucosidase BglC; Belongs to the glycosyl hydrolase 1 family.
 
 
 0.988
pagL
Phospho-alpha-glucosidase PagL.
 
 
 0.911
lacC
Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.877
ptsH
Phosphocarrier protein HPr.
   
 0.728
crh
HPr-like protein Crh.
   
 0.728
treB
PTS system trehalose-specific EIIBC component.
  
  
 0.625
ptsG
PTS system glucose-specific EIICBA component.
  
  
 0.606
sacY
Levansucrase and sucrase synthesis operon antiterminator.
 
  
 0.604
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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