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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydaM_2Putative diguanylate cyclase YdaM. (350 aa)    
Predicted Functional Partners:
kinE
Sporulation kinase E.
 
 0.996
gmr
Cyclic di-GMP phosphodiesterase Gmr.
 
0.995
ydaM_1
Putative diguanylate cyclase YdaM.
 
0.994
OPJ56036.1
Blue-light-activated protein.
 
 
 0.988
cph2
Phytochrome-like protein cph2.
 
 
 0.987
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.941
rpfG_3
Cyclic di-GMP phosphodiesterase response regulator RpfG.
 
0.928
ribBA
Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.910
rpfG_2
Cyclic di-GMP phosphodiesterase response regulator RpfG.
 0.907
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.900
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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