Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OPJ55386.1Hypothetical protein. (263 aa)    
Predicted Functional Partners:
thiI
Putative tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
   
 0.655
ttcA
tRNA 2-thiocytidine biosynthesis protein TtcA; Belongs to the TtcA family.
       0.522
uvsE
UV DNA damage endonuclease.
 
     0.479
pheT
phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.456
mleN_2
malate-2H(+)/Na(+)-lactate antiporter.
       0.447
cph2
Phytochrome-like protein cph2.
       0.441
OPJ56057.1
Hypothetical protein.
   
    0.423
ykuD
Putative L,D-transpeptidase YkuD.
       0.423
ypdB
Transcriptional regulatory protein YpdB.
  
    0.419
OPJ57077.1
Sepiapterin reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.416
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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