STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpfG_2Cyclic di-GMP phosphodiesterase response regulator RpfG. (398 aa)    
Predicted Functional Partners:
ydaM_2
Putative diguanylate cyclase YdaM.
 0.907
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.906
ribBA
Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.903
ydaM_1
Putative diguanylate cyclase YdaM.
 0.813
adrA
Putative diguanylate cyclase AdrA.
 0.793
cph2
Phytochrome-like protein cph2.
 
 0.790
yegE
Putative diguanylate cyclase YegE.
 0.767
gmr
Cyclic di-GMP phosphodiesterase Gmr.
   
 0.745
relA
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.736
folE
GTP cyclohydrolase 1.
    
  0.718
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.