Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rpfG_2Cyclic di-GMP phosphodiesterase response regulator RpfG. (398 aa)    
Predicted Functional Partners:
ribBA
Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.874
ydaM_2
Putative diguanylate cyclase YdaM.
 
 
 0.837
folE
GTP cyclohydrolase 1.
    
  0.782
cph2
Phytochrome-like protein cph2.
 
 
 0.781
adrA
Putative diguanylate cyclase AdrA.
 
 0.755
ydaM_1
Putative diguanylate cyclase YdaM.
 
 
 0.743
relA
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.729
yegE
Putative diguanylate cyclase YegE.
 
 0.724
gmr
Cyclic di-GMP phosphodiesterase Gmr.
 
   
 0.699
yjbM
GTP pyrophosphokinase YjbM.
     
  0.688
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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