| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OPJ55463.1 | OPJ55464.1 | CLOTH_15260 | CLOTH_15270 | YtxH-like protein. | Hypothetical protein. | 0.773 |
| OPJ55463.1 | gyrA | CLOTH_15260 | CLOTH_15250 | YtxH-like protein. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.552 |
| OPJ55463.1 | gyrB | CLOTH_15260 | CLOTH_15240 | YtxH-like protein. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.452 |
| OPJ55463.1 | rsbV | CLOTH_15260 | CLOTH_15280 | YtxH-like protein. | anti-sigma-B factor antagonist; Belongs to the anti-sigma-factor antagonist family. | 0.806 |
| OPJ55463.1 | rsbW | CLOTH_15260 | CLOTH_15290 | YtxH-like protein. | Serine-protein kinase RsbW. | 0.823 |
| OPJ55463.1 | sigB | CLOTH_15260 | CLOTH_15300 | YtxH-like protein. | RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. | 0.779 |
| OPJ55464.1 | OPJ55463.1 | CLOTH_15270 | CLOTH_15260 | Hypothetical protein. | YtxH-like protein. | 0.773 |
| OPJ55464.1 | gyrA | CLOTH_15270 | CLOTH_15250 | Hypothetical protein. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.538 |
| OPJ55464.1 | gyrB | CLOTH_15270 | CLOTH_15240 | Hypothetical protein. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.446 |
| OPJ55464.1 | rsbV | CLOTH_15270 | CLOTH_15280 | Hypothetical protein. | anti-sigma-B factor antagonist; Belongs to the anti-sigma-factor antagonist family. | 0.773 |
| OPJ55464.1 | rsbW | CLOTH_15270 | CLOTH_15290 | Hypothetical protein. | Serine-protein kinase RsbW. | 0.773 |
| OPJ55464.1 | sigB | CLOTH_15270 | CLOTH_15300 | Hypothetical protein. | RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. | 0.773 |
| gyrA | OPJ55463.1 | CLOTH_15250 | CLOTH_15260 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | YtxH-like protein. | 0.552 |
| gyrA | OPJ55464.1 | CLOTH_15250 | CLOTH_15270 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Hypothetical protein. | 0.538 |
| gyrA | gyrB | CLOTH_15250 | CLOTH_15240 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.999 |
| gyrA | rsbV | CLOTH_15250 | CLOTH_15280 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | anti-sigma-B factor antagonist; Belongs to the anti-sigma-factor antagonist family. | 0.636 |
| gyrA | rsbW | CLOTH_15250 | CLOTH_15290 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Serine-protein kinase RsbW. | 0.609 |
| gyrA | sigB | CLOTH_15250 | CLOTH_15300 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. | 0.666 |
| gyrB | OPJ55463.1 | CLOTH_15240 | CLOTH_15260 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | YtxH-like protein. | 0.452 |
| gyrB | OPJ55464.1 | CLOTH_15240 | CLOTH_15270 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Hypothetical protein. | 0.446 |