Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rsbVanti-sigma-B factor antagonist; Belongs to the anti-sigma-factor antagonist family. (105 aa)    
Predicted Functional Partners:
rsbW
Serine-protein kinase RsbW.
 
 0.999
sigB
RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family.
 
 
 0.984
rsbP
Phosphoserine phosphatase RsbP.
 
 0.983
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 0.968
fliN
Flagellar motor switch protein FliN.
  
   0.936
OPJ56800.1
Hypothetical protein.
  
 0.912
OPJ56036.1
Blue-light-activated protein.
  
 
 0.905
flgE
Flagellar hook protein FlgE.
   
    0.904
OPJ56066.1
Flagellar rod assembly protein/muramidase FlgJ.
   
    0.904
flgB
Flagellar basal body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.896
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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