ywlF protein (Clostridium thermoalcaliphilum)

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Score

ywlF

Putative sugar phosphate isomerase YwlF. (149 aa)

Predicted Functional Partners:

glyA

0.963

upp

0.954

rpe

0.942

nifJ

0.936

prs_2

0.911

rbsK

0.907

deoB

0.891

dxs_2

0.884

tktA

0.880

lacC

0.877

Your Current Organism:

Clostridium thermoalcaliphilum

NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
deoB	dxs_2	CLOTH_02480	CLOTH_15460	Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.	1-deoxy-D-xylulose-5-phosphate synthase.	0.867
deoB	prs_2	CLOTH_02480	CLOTH_17450	Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.	Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.	0.891
deoB	rbsK	CLOTH_02480	CLOTH_03100	Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	0.857
deoB	tktA	CLOTH_02480	CLOTH_15470	Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.	Transketolase 1.	0.871
deoB	ywlF	CLOTH_02480	CLOTH_15750	Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.	Putative sugar phosphate isomerase YwlF.	0.891
dxs_2	deoB	CLOTH_15460	CLOTH_02480	1-deoxy-D-xylulose-5-phosphate synthase.	Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.	0.867
dxs_2	nifJ	CLOTH_15460	CLOTH_01250	1-deoxy-D-xylulose-5-phosphate synthase.	Pyruvate-flavodoxin oxidoreductase.	0.869
dxs_2	prs_2	CLOTH_15460	CLOTH_17450	1-deoxy-D-xylulose-5-phosphate synthase.	Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.	0.875
dxs_2	rbsK	CLOTH_15460	CLOTH_03100	1-deoxy-D-xylulose-5-phosphate synthase.	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	0.873
dxs_2	rpe	CLOTH_15460	CLOTH_01960	1-deoxy-D-xylulose-5-phosphate synthase.	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.	0.935
dxs_2	tktA	CLOTH_15460	CLOTH_15470	1-deoxy-D-xylulose-5-phosphate synthase.	Transketolase 1.	0.999
dxs_2	ywlF	CLOTH_15460	CLOTH_15750	1-deoxy-D-xylulose-5-phosphate synthase.	Putative sugar phosphate isomerase YwlF.	0.884
glyA	nifJ	CLOTH_00660	CLOTH_01250	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Pyruvate-flavodoxin oxidoreductase.	0.744
glyA	upp	CLOTH_00660	CLOTH_15740	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.842
glyA	ywlF	CLOTH_00660	CLOTH_15750	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Putative sugar phosphate isomerase YwlF.	0.963
lacC	nifJ	CLOTH_00990	CLOTH_01250	Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.	Pyruvate-flavodoxin oxidoreductase.	0.505
lacC	rbsK	CLOTH_00990	CLOTH_03100	Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	0.452
lacC	rpe	CLOTH_00990	CLOTH_01960	Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.	0.515
lacC	tktA	CLOTH_00990	CLOTH_15470	Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.	Transketolase 1.	0.400
lacC	ywlF	CLOTH_00990	CLOTH_15750	Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.	Putative sugar phosphate isomerase YwlF.	0.877