Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lnpDUDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (342 aa)    
Predicted Functional Partners:
gtaB
UTP--glucose-1-phosphate uridylyltransferase.
 
  
 0.974
glmU
Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
   
 0.932
epsH
Putative glycosyltransferase EpsH.
 
   
 0.891
puuR
HTH-type transcriptional regulator PuuR.
  
 
 0.859
epsD
Putative glycosyltransferase EpsD.
 
  
 0.842
OPJ55312.1
Polysaccharide biosynthesis protein.
     
 0.825
OPJ55315.1
Glycosyl transferases group 1.
    
 0.815
ndhI_3
NAD(P)H-quinone oxidoreductase subunit I.
 
     0.814
OPJ55313.1
Polysaccharide pyruvyl transferase.
       0.784
OPJ55316.1
O-antigen ligase.
     
 0.745
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.