glpE protein (Clostridium thermoalcaliphilum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

glpE

Thiosulfate sulfurtransferase GlpE. (104 aa)

Predicted Functional Partners:

puuB

0.953

sodB

0.952

OPJ56775.1

0.917

OPJ55937.1

0.917

rpsQ

0.915

rplQ

0.913

rplO

0.907

rplC

0.906

rplM

0.904

ppiB

0.898

Your Current Organism:

Clostridium thermoalcaliphilum

NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OPJ55937.1	glpE	CLOTH_11150	CLOTH_16410	Putative metallo-hydrolase.	Thiosulfate sulfurtransferase GlpE.	0.917
OPJ55937.1	rpsQ	CLOTH_11150	CLOTH_18500	Putative metallo-hydrolase.	30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.	0.494
OPJ56775.1	glpE	CLOTH_00570	CLOTH_16410	Putative metallo-hydrolase.	Thiosulfate sulfurtransferase GlpE.	0.917
OPJ56775.1	rpsQ	CLOTH_00570	CLOTH_18500	Putative metallo-hydrolase.	30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.	0.494
glpE	OPJ55937.1	CLOTH_16410	CLOTH_11150	Thiosulfate sulfurtransferase GlpE.	Putative metallo-hydrolase.	0.917
glpE	OPJ56775.1	CLOTH_16410	CLOTH_00570	Thiosulfate sulfurtransferase GlpE.	Putative metallo-hydrolase.	0.917
glpE	ppiB	CLOTH_16410	CLOTH_11270	Thiosulfate sulfurtransferase GlpE.	Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.898
glpE	puuB	CLOTH_16410	CLOTH_08830	Thiosulfate sulfurtransferase GlpE.	Gamma-glutamylputrescine oxidoreductase.	0.953
glpE	rplC	CLOTH_16410	CLOTH_18590	Thiosulfate sulfurtransferase GlpE.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.906
glpE	rplM	CLOTH_16410	CLOTH_18240	Thiosulfate sulfurtransferase GlpE.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.904
glpE	rplO	CLOTH_16410	CLOTH_18400	Thiosulfate sulfurtransferase GlpE.	50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.907
glpE	rplQ	CLOTH_16410	CLOTH_18290	Thiosulfate sulfurtransferase GlpE.	50S ribosomal protein L17.	0.913
glpE	rpsQ	CLOTH_16410	CLOTH_18500	Thiosulfate sulfurtransferase GlpE.	30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.	0.915
glpE	sodB	CLOTH_16410	CLOTH_00350	Thiosulfate sulfurtransferase GlpE.	Superoxide dismutase.	0.952
ppiB	glpE	CLOTH_11270	CLOTH_16410	Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	Thiosulfate sulfurtransferase GlpE.	0.898
ppiB	rplC	CLOTH_11270	CLOTH_18590	Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.841
ppiB	rplM	CLOTH_11270	CLOTH_18240	Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.855
ppiB	rplO	CLOTH_11270	CLOTH_18400	Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.857
ppiB	rplQ	CLOTH_11270	CLOTH_18290	Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	50S ribosomal protein L17.	0.854
ppiB	rpsQ	CLOTH_11270	CLOTH_18500	Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.	0.858