| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ispE | rnmV | CLOTH_19210 | CLOTH_17330 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. | 0.644 |
| ispE | rsmA | CLOTH_19210 | CLOTH_17340 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.936 |
| ispE | yocH | CLOTH_19210 | CLOTH_17320 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Cell wall-binding protein YocH precursor. | 0.804 |
| rnmV | ispE | CLOTH_17330 | CLOTH_19210 | Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.644 |
| rnmV | rsmA | CLOTH_17330 | CLOTH_17340 | Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.947 |
| rnmV | yocH | CLOTH_17330 | CLOTH_17320 | Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. | Cell wall-binding protein YocH precursor. | 0.871 |
| rpsB | rpsD | CLOTH_04020 | CLOTH_18310 | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.999 |
| rpsB | rpsE | CLOTH_04020 | CLOTH_18420 | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.999 |
| rpsB | rpsH | CLOTH_04020 | CLOTH_18450 | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. | 0.999 |
| rpsB | rpsJ | CLOTH_04020 | CLOTH_18600 | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.999 |
| rpsB | rpsQ | CLOTH_04020 | CLOTH_18500 | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.999 |
| rpsB | rpsS | CLOTH_04020 | CLOTH_18550 | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.999 |
| rpsB | rsmA | CLOTH_04020 | CLOTH_17340 | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.914 |
| rpsD | rpsB | CLOTH_18310 | CLOTH_04020 | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.999 |
| rpsD | rpsE | CLOTH_18310 | CLOTH_18420 | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.999 |
| rpsD | rpsH | CLOTH_18310 | CLOTH_18450 | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. | 0.999 |
| rpsD | rpsJ | CLOTH_18310 | CLOTH_18600 | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.999 |
| rpsD | rpsQ | CLOTH_18310 | CLOTH_18500 | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.999 |
| rpsD | rpsS | CLOTH_18310 | CLOTH_18550 | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.999 |
| rpsD | rsmA | CLOTH_18310 | CLOTH_17340 | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.928 |