Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
betIHTH-type transcriptional regulator BetI. (214 aa)    
Predicted Functional Partners:
grdI
Betaine reductase complex component B subunit alpha.
 
     0.843
grdH_1
Betaine reductase complex component B subunit beta.
 
     0.769
grdH_2
Betaine reductase complex component B subunit beta.
 
     0.724
OPJ56261.1
Hypothetical protein.
  
     0.630
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
   
    0.572
kinE
Sporulation kinase E.
    
 
 0.557
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.534
adhE
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
     
 0.527
purL
Phosphoribosylformylglycinamidine synthase 2.
      
 0.524
OPJ56036.1
Blue-light-activated protein.
      
 0.488
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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