Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OPJ54983.1Gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (359 aa)    
Predicted Functional Partners:
OPJ54982.1
glmZ(sRNA)-inactivating NTPase; Displays ATPase and GTPase activities.
  
  
 0.981
whiA
Sporulation transcription regulator WhiA; Involved in cell division and chromosome segregation.
  
  
 0.882
polX
DNA polymerase/3'-5' exonuclease PolX.
       0.777
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
       0.749
ndx1_2
Diadenosine hexaphosphate hydrolase; Belongs to the Nudix hydrolase family.
  
    0.705
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
   0.605
dnaE
DNA polymerase III subunit alpha.
       0.572
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
       0.565
crh
HPr-like protein Crh.
  
  
 0.550
albA_1
Albonoursin synthase.
  
 
 0.546
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.