dnaE protein (Clostridium thermoalcaliphilum)

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Predicted Interactions

gene neighborhood

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gene co-occurrence

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textmining

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protein homology

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Score

dnaE

DNA polymerase III subunit alpha. (1159 aa)

Predicted Functional Partners:

dnaN

0.991

OPJ55594.1

0.990

dnaX_2

0.987

dnaX_1

0.985

polC_2

0.922

ssbA_2

0.901

ssbA_1

0.885

guaA

0.805

pyk

0.801

polA_1

0.747

Your Current Organism:

Clostridium thermoalcaliphilum

NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OPJ55594.1	dnaE	CLOTH_13530	CLOTH_17990	DNA polymerase III subunit delta.	DNA polymerase III subunit alpha.	0.990
OPJ55594.1	dnaN	CLOTH_13530	CLOTH_15210	DNA polymerase III subunit delta.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.994
OPJ55594.1	dnaX_1	CLOTH_13530	CLOTH_17060	DNA polymerase III subunit delta.	DNA polymerase III subunit tau.	0.994
OPJ55594.1	dnaX_2	CLOTH_13530	CLOTH_20000	DNA polymerase III subunit delta.	DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.993
OPJ55594.1	polA_1	CLOTH_13530	CLOTH_12690	DNA polymerase III subunit delta.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.731
OPJ55594.1	polC_2	CLOTH_13530	CLOTH_04120	DNA polymerase III subunit delta.	DNA polymerase III PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.916
dnaE	OPJ55594.1	CLOTH_17990	CLOTH_13530	DNA polymerase III subunit alpha.	DNA polymerase III subunit delta.	0.990
dnaE	dnaN	CLOTH_17990	CLOTH_15210	DNA polymerase III subunit alpha.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.991
dnaE	dnaX_1	CLOTH_17990	CLOTH_17060	DNA polymerase III subunit alpha.	DNA polymerase III subunit tau.	0.985
dnaE	dnaX_2	CLOTH_17990	CLOTH_20000	DNA polymerase III subunit alpha.	DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.987
dnaE	guaA	CLOTH_17990	CLOTH_11700	DNA polymerase III subunit alpha.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.805
dnaE	polA_1	CLOTH_17990	CLOTH_12690	DNA polymerase III subunit alpha.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.747
dnaE	polC_2	CLOTH_17990	CLOTH_04120	DNA polymerase III subunit alpha.	DNA polymerase III PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.922
dnaE	pyk	CLOTH_17990	CLOTH_18010	DNA polymerase III subunit alpha.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.801
dnaE	ssbA_1	CLOTH_17990	CLOTH_08160	DNA polymerase III subunit alpha.	Single-stranded DNA-binding protein A.	0.885
dnaE	ssbA_2	CLOTH_17990	CLOTH_14990	DNA polymerase III subunit alpha.	Single-stranded DNA-binding protein A.	0.901
dnaN	OPJ55594.1	CLOTH_15210	CLOTH_13530	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III subunit delta.	0.994
dnaN	dnaE	CLOTH_15210	CLOTH_17990	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III subunit alpha.	0.991
dnaN	dnaX_1	CLOTH_15210	CLOTH_17060	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III subunit tau.	0.991
dnaN	dnaX_2	CLOTH_15210	CLOTH_20000	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.994