STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysE_1Serine acetyltransferase. (79 aa)    
Predicted Functional Partners:
cysK
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.996
cysS
cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.984
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.902
sdhB
L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.892
sdhA
L-serine dehydratase, alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.892
tdcB
L-threonine dehydratase catabolic TdcB.
     
 0.869
mrnC
Mini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family.
  
  
 0.865
trpB
Tryptophan synthase beta chain.
  
 0.856
nadA
Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
  
    0.787
mdeA
Methionine gamma-lyase.
  
 
 0.755
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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