OPJ54791.1 protein (Clostridium thermoalcaliphilum)

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Score

OPJ54791.1

Permease family protein. (501 aa)

Predicted Functional Partners:

purL

0.802

xpt

0.750

OPJ55825.1

0.644

yedA

0.539

purE_1

0.519

mprF

0.514

purK

0.507

guaA

0.452

purM

0.424

purD

0.421

Your Current Organism:

Clostridium thermoalcaliphilum

NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OPJ54791.1	OPJ55825.1	CLOTH_19100	CLOTH_10030	Permease family protein.	Nicotianamine synthase protein.	0.644
OPJ54791.1	guaA	CLOTH_19100	CLOTH_11700	Permease family protein.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.452
OPJ54791.1	mprF	CLOTH_19100	CLOTH_10020	Permease family protein.	Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.514
OPJ54791.1	purD	CLOTH_19100	CLOTH_11630	Permease family protein.	Phosphoribosylamine--glycine ligase; Belongs to the GARS family.	0.421
OPJ54791.1	purE_1	CLOTH_19100	CLOTH_07640	Permease family protein.	N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	0.519
OPJ54791.1	purK	CLOTH_19100	CLOTH_07630	Permease family protein.	N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).	0.507
OPJ54791.1	purL	CLOTH_19100	CLOTH_11620	Permease family protein.	Phosphoribosylformylglycinamidine synthase 2.	0.802
OPJ54791.1	purM	CLOTH_19100	CLOTH_11660	Permease family protein.	Phosphoribosylformylglycinamidine cyclo-ligase.	0.424
OPJ54791.1	xpt	CLOTH_19100	CLOTH_19090	Permease family protein.	Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.	0.750
OPJ54791.1	yedA	CLOTH_19100	CLOTH_19110	Permease family protein.	Putative inner membrane transporter YedA.	0.539
OPJ55825.1	OPJ54791.1	CLOTH_10030	CLOTH_19100	Nicotianamine synthase protein.	Permease family protein.	0.644
OPJ55825.1	mprF	CLOTH_10030	CLOTH_10020	Nicotianamine synthase protein.	Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.960
guaA	OPJ54791.1	CLOTH_11700	CLOTH_19100	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Permease family protein.	0.452
guaA	purD	CLOTH_11700	CLOTH_11630	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylamine--glycine ligase; Belongs to the GARS family.	0.942
guaA	purE_1	CLOTH_11700	CLOTH_07640	GMP synthase; Catalyzes the synthesis of GMP from XMP.	N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	0.762
guaA	purK	CLOTH_11700	CLOTH_07630	GMP synthase; Catalyzes the synthesis of GMP from XMP.	N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).	0.783
guaA	purL	CLOTH_11700	CLOTH_11620	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylformylglycinamidine synthase 2.	0.993
guaA	purM	CLOTH_11700	CLOTH_11660	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylformylglycinamidine cyclo-ligase.	0.863
guaA	xpt	CLOTH_11700	CLOTH_19090	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.	0.984
mprF	OPJ54791.1	CLOTH_10020	CLOTH_19100	Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	Permease family protein.	0.514