| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carA | carB | CLOTH_11420 | CLOTH_11410 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Carbamoyl-phosphate synthase large chain. | 0.999 |
| carA | glmS | CLOTH_11420 | CLOTH_20310 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.903 |
| carA | purF | CLOTH_11420 | CLOTH_11670 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.960 |
| carA | purL | CLOTH_11420 | CLOTH_11620 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase 2. | 0.995 |
| carB | carA | CLOTH_11410 | CLOTH_11420 | Carbamoyl-phosphate synthase large chain. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.999 |
| carB | glmS | CLOTH_11410 | CLOTH_20310 | Carbamoyl-phosphate synthase large chain. | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.929 |
| carB | purF | CLOTH_11410 | CLOTH_11670 | Carbamoyl-phosphate synthase large chain. | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.980 |
| carB | purL | CLOTH_11410 | CLOTH_11620 | Carbamoyl-phosphate synthase large chain. | Phosphoribosylformylglycinamidine synthase 2. | 0.964 |
| glcB | glmM | CLOTH_06680 | CLOTH_20300 | PTS system glucoside-specific EIICBA component. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.914 |
| glcB | glmS | CLOTH_06680 | CLOTH_20310 | PTS system glucoside-specific EIICBA component. | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.961 |
| glcB | glmU | CLOTH_06680 | CLOTH_17440 | PTS system glucoside-specific EIICBA component. | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.514 |
| glcB | nagB | CLOTH_06680 | CLOTH_03520 | PTS system glucoside-specific EIICBA component. | Glucosamine-6-phosphate deaminase 1; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.976 |
| glcB | pgi | CLOTH_06680 | CLOTH_07540 | PTS system glucoside-specific EIICBA component. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.971 |
| glcB | ptsG | CLOTH_06680 | CLOTH_07680 | PTS system glucoside-specific EIICBA component. | PTS system glucose-specific EIICBA component. | 0.999 |
| glmM | glcB | CLOTH_20300 | CLOTH_06680 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | PTS system glucoside-specific EIICBA component. | 0.914 |
| glmM | glmS | CLOTH_20300 | CLOTH_20310 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.993 |
| glmM | glmU | CLOTH_20300 | CLOTH_17440 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.991 |
| glmM | nagB | CLOTH_20300 | CLOTH_03520 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucosamine-6-phosphate deaminase 1; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.922 |
| glmM | pgi | CLOTH_20300 | CLOTH_07540 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.753 |
| glmM | ptsG | CLOTH_20300 | CLOTH_07680 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | PTS system glucose-specific EIICBA component. | 0.914 |